Nutraceutical Horticulture : An overview of biochemical and molecular considerations

Authors

  • G N MohanKumar Washington State University Author

DOI:

https://doi.org/10.24154/jhs.v17i1.2175

Keywords:

Cellular components, Transcription factors, Tumor Necrosis Factor, Molecular pathways, phytochemicals, Nutraceutical

Abstract

The major components of our diet, namely, carbohydrates, fats, proteins, vitamins, and minerals provide for the building blocks besides serving as metabolic fuel to fulfil the bioenergetic needs. Since they serve the basic cellular needs, they are considered as ‘primary metabolites’. The molecular and biochemical pathways modulated by the major food components of our diet are well-established. Many phytochemicals referred to as ‘secondary metabolites’ and not considered as an ‘essential part’ of our diet, also find their way into the digestive tract along with the major food components. Interest in the role played by the ‘non-essential’ or ‘minor’ components of our diet in preventing the initiation or progression of metabolic disorders has gained momentum. The metabolic disorders, by and large, are non-pathogenic in nature and originate as a consequence of derailed cellular metabolism.

References

Anand, P., Kunnumakkara, A.B., Sundaram, C, Harikumar, K.B., Tharakan, S.T., Lai, O.S., Sung, B., Aggarwal, B.B. 2008. Cancer is a preventable disease that requires major lifestyle changes. Pharm Res, 25:2097-116 DOI: https://doi.org/10.1007/s11095-008-9661-9

Taniguchi, K., Karin, M. 2018. NF-κB, inflammation, immunity and cancer: Coming of age. Nat Rev Immunol 18, 309–324. DOI: https://doi.org/10.1038/nri.2017.142

Liu, T., Zhang, L., Joo, D., Sun, S.C. 2017. NF-κB signaling in inflammation. Sig Transduct Target Ther 2, 17023 DOI: https://doi.org/10.1038/sigtrans.2017.23

Holbrook, J. Lara-Reyna, S., Jarosz-Griffiths, H., McDermott, M. 2019. Tumour necrosis factor signaling in health and disease. F1000Res. 28: F1000 Faculty Rev-111. doi:10.12688/f1000research. 17023.1 DOI: https://doi.org/10.12688/f1000research.17023.1

Downloads

Published

30-06-2022

Issue

Section

Review

How to Cite

MohanKumar, G. N. (2022). Nutraceutical Horticulture : An overview of biochemical and molecular considerations. Journal of Horticultural Sciences, 17(1), 1-5. https://doi.org/10.24154/jhs.v17i1.2175

Similar Articles

1-10 of 113

You may also start an advanced similarity search for this article.